Euler is a new approach to fragment assembly that abandons the classical "overlap - layout - consensus"  paradigm that is used in all currently available assembly tools. See EULER papers for details.

For the last twenty years, fragment assembly in DNA sequencing followed the "overlap - layout - consensus"  paradigm that is used in all currently available assembly tools. Although this approach proved to be useful in  assembling clones, it faces difficulties in genomic shotgun  assembly:  the existing algorithms make assembly shortcomings and are often unable to resolve repeats even in prokaryotic genomes. Biologists are well-aware of  these errors and are forced to carry out additional experiments to verify the assembled contigs.

We abandon the classical  "overlap - layout - consensus"  approach in favor of a new Eulerian Superpath approach. EULER, in contrast to the Celera assembler, does not mask repeats but uses them instead as a powerful fragment assembly tool. This EULER server provides an online tool to assemble DNA sequences.

The developers of EULER make no claims about the suitability or accuracy of this software or data for any purpose, and make no warranties, either expressed or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. The software and data are provided "As Is".

This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior written permission.